INDICES> policosanol (4)

["Dr.L.Offerhaus" <lo@euronet.nl>]

INDICES> policosanol (4)
-------------------------------

Dear friends,

As was to be expected the level of evidence was poor. The most recent
clinical publication (Berthold and Berthold, Am Heart J 2002;143:356-65),
which was presented at a promotional symposium, clearly states: "Data on
efficacy determined by clinical end points such as rates of cardiac events
or
cardiac mortality are lacking". In addition there is a registration hurdle
to take
because apparently the stuff is "a mixture of...  .....alcohols isolated
from
sugar cane wax" - and it is uncertain whether it can ever be marketed in
such
a constant composition that the FDA is satisfied. It MAY become a good
drug, but let's wait. Safety data for a limited number of patients are now
available up to 3 years.

The text obtained from Ms Amador is clearly promotional and does not
belong on INDICES.

Regards,

Dr.L.Offerhaus
Koedijklaan 1a
NL-1406 KW Bussum
The Netherlands
Phone +31-35-6923288 Fax +31-35-6923277
lo@euronet.nl



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