INDICES> 4th generation cephalosporins (2)

["Prouty, Gregory" <gprouty@msx.ndc.mc.uci.edu>]

INDICES> 4th generation cephalosporins (2)
-----------------------------------------------------

Cefepime should be reserved as a secondary line agent for infections where
pseudomonas is of concern.  

Absolutely not as surgical prophylaxis.  

For dirty surgeries other agents should be available - depends on site of
surgery.  Certainly, ampicillin, gentamicin with clindamycin would provide
terrific coverage plus or minus metronidazole.  

If you don't control cefepime now, your pseudomonas will develop 
resistance, quickly.

Greg Prouty, Pharm.D.
University of California, Irvine Medical Center
Orange, California  
USA
gprouty@msx.ndc.mc.uci.edu

[thanks, Greg, for giving a clear answer! WB]


--
To send a message to Indices, write to: indices@usa.healthnet.org
To subscribe or unsubscribe, write to: majordomo@usa.healthnet.org
in the body of the message type: subscribe indices OR unsubscribe indices
To contact a person, send a message to: indices-help@usa.healthnet.org
Information and archives: http://www.healthnet.org/programs/indices.html