INDICES> interaction between lamotrigine and quetiapine?

["Joe Talmud" <jtalmud@uctgsh1.uct.ac.za>]

INDICES: interaction between lamotrigine and quetiapine?
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Hi

Can anyone tell us whether there is a drug interaction between 
lamotrigine (being used as a mood stabiliser) and quetiapine (being 
used for its antimanic activity) in our 35 year old male patient?

It seems that quetiapine is metabolised by cyp 3A4 and can inhibit 
3A4 and  2C9, but we're unable to find whether lamotrigine is 
Cyp-metabolised. Any suggestions?

Thanks

Joe Talmud
Drug Information Pharmacist
Medicines Information Centre
Dept Pharmacology, University of Cape Town Med School
K Floor, Old Main Building, Groote Schuur Hospital,
Observatory 7925
South Africa
Phone 021-4066427 Fax 27 21 4480503
e-mail  jtalmud@uctgsh1.uct.ac.za


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