INDICES> unstability of cotrimoxazole suspension

[msd-mtwara <msd-mtwara@twiga.com>]

INDICES> unstability of cotrimoxazole suspension
------------------------------------------------

dear Indices

We are procuring and distributing large amounts of
medicine every time. It has happened several times that some batches of
Cotrimoxazole suspension will loose its stability.
This will be shown by change of colour of the product while still 
within the stated shelf time.
Before I certained that might be because of storage conditions but their is no
strict control of storage condition far from temperature and light.
Can any one tell me what might be the cause of these?

Peter Ruzangi-pharmacist
Zonal Medical Store department
P.O. Box 646
Tel.023 2333316 
Fax.023 2333989
MTWARA. 
TANZANIA-EAST AFRICA

Email: msd-mtwara@twiga.com

[Peter, hard to say from a distance what is the problem. Could be the screwcap, bad/poor
formulation, counterfeit? Did you consider sending some "normal" and "abnormal" looking 
bottles back to a Quality Control laboratory? WB]
--
Send mail for the `INDICES' conference to `indices@usa.healthnet.org'.
Mail administrative requests to `majordomo@usa.healthnet.org'.
For additional assistance, send mail to:  `owner-indices@usa.healthnet.org'.