INDICES> Topical Cidofovir

["Kristján Linnet" <krisline@landspitali.is>]

INDICES> Topical Cidofovir
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We have a HIV patient at our hospital with a genital herpes infection
resistant to both acyclovir and foscarnet treatment. Cidofovir might be an
alternative, so we would like to ask if anyone could supply information on
the formulation of a topical preparation of cidofovir (ca 1% gel or cream)
from a sterile solution of 75 mg/ml. Is propylene glycol a necessary
ingredient of the vehicle? Could Locobase be used as a vehicle? Or K-Y
lubricating jelly?

Thanks in advance

Kristján Linnet
The Hospital Pharmacy
Landspitali - University Hospital
Fossvogi - 108 Reykjavik - Iceland 
E-mail: krisline@landspitali.is
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