INDICES> Steven JohnsonSyndrome (2)

[helpline <helpline@best.net.pk>]

INDICES> Steven JohnsonSyndrome (2)
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[2 responses into 1 message; WB]

Dear Ningraswani,

Below is the list of drugs that can cause Steven- Johnsons syndrome. Those drugs
most closely associated with causing Stevens-Johnson syndrome are antibacterial
sulfonamides, anticonvulsants, oxicam non-steroidal antiinflammatory agents
(piroxicam and tenoxicam), chlormezanone and allopurinol. This particular
drug-induced adverse skin reaction is potentially fatal.

Drugs implicated in causing Stevens-Johnson syndrome:
A.  ALLOPURINOL
B.  AMPICILLIN
C.  ARSENIC
D.  ASTEMIZOLE
E.  BARBITURATES
F.  BELLADONNA
G.  BROMIDES
H.  CARBAMAZEPINE
I.  CEPHALOSPORINS
J.  CHLORAMPHENICOL
K.  CHLORMEZANONE
K.  CHLOROQUINE
L.  CHLORPROPAMIDE
 1. One case of Stevens-Johnson syndrome in association with
    conjunctivitis has been reported in a 71-year-old female
    receiving 500 to 1000 mg/day of chlorpropamide for
    approximately two weeks .
M.  CIMETIDINE
N.  CIPROFLOXACIN
O.  CLINDAMYCIN
P.  CLOFIBRATE
Q.  CODEINE
R.  COTRIMOXAZOLE
S.  CYCLOSERINE
T.  DIDANOSINE
U.  DIFLUNISAL
V.  DIGITALIS
W.  DILTIAZEM
X.  DOXYCYCLINE
Y.  ERYTHROMYCIN
Z.  ETHOSUXIMIDE
AA. FENOPROFEN
BB. FLUCONAZOLE
CC. FUROSEMIDE
DD. GOLD SALTS
EE. GRISEOFULVIN
FF. HYDRALAZINE
GG. IBUPROFEN
HH. INDAPAMIDE
II. IODIDES
JJ. ISONIAZID
KK. KETOPROFEN
LL. MACROLIDE ANTIBIOTICS
1.  Includes roxithromycin, spiramycin, erythromycin, and
    josamycin
MM. MEASLES VACCINE
NN. MECHLORETHAMIDE (Nitrogen Mustard)

OO. MEFLOQUINE
PP. MEPROBAMATE
QQ. MERCURIALS
RR. METHAZOLAMIDE
SS. MINOCYCLINE
TT. MINOXIDIL
UU. NORFLOXACIN
VV. NYSTATIN
WW. OFLAXACIN
XX. ORAL CONTRACEPTIVES
YY. PARAMETHADIONE
ZZ. PEFLOXACIN
AB. PENICILLIN
AC. PHENACETIN
AD. PHENOBARBITAL
AE. PHENOTHIAZINES
AF. PHENYLBUTAZONE
AG. PHENYTOIN
AH. PIROXICAM
AI. QUININE
AJ. RIFAMPIN
AK. SALICYLATES
AL. SUCCINIMIDE
AM. SULFONAMIDES
 1. Trimethoprim-sulfamethoxazole-sulfadiazine,
    sulfasalazine
AN. SULINDAC
AO. SULTAMICILLIN
AP. TENOXICAM
AQ. TERBENAFINE
AR. TETRACYCLINE
AS. THIAZIDES
AT. THIOURACIL
AU. VALPROIC ACID
AV. VANCOMYCIN
AW. VERAPAMIL


Regards.

Ayesha Ahmed
Drug Information Helpline
Pakistan

Email: helpline@best.net.pk  [added by moderator; please include email in signature! Thanks WB]

------

From: Yulia Trisna <lia23@centrin.net.id>

Drugs associated with Stevens-Johnson syndrome:

Allopurinol + Captopril/Enalapril
Anticonvulsants (Carbamazepine, Ethosuximide, Felbamate, Lamotrigine,
Phenytoin)
Azoles (Fluconazole, Itraconazole)
Cephalosporins (Cefixime, Ceftazidime, Cefuroxime)
Chlorambucil
Clindamycin
Danazol
Delavirdine
Imipenem-Cilastatin
Erythromycin
Minoxidil
Nevirapine
NSAIDs (Ketorolac)
Nystatin
Penicillins
Pentamidine
Quinolones (Ofloxacin)
Saquinavir
Sulfomamides
Terbinafine
Terfenadine
Thiabendazole
Ticlopidine
Tocainide
Vaccines (diphteria/typhoid, BCG, OPV, Hepatitis B)


Hope this helps.

Regards,
Yulia Trisna
-- 
Department of Pharmacy
Cipto Mangunkusumo Hospital
Jakarta-Indonesia
Tel. 62 21 331688
Fax. 62 21 3143580
http://centrin.net.id/~farmasi/
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