[india-drug] Response to Toxicity of nimesulide

["J.S. Bapna" <jbapna@iihmr.org>]

Response to Toxicity of nimesulide 
----------------------------------

Dear Dr. Gupta,

Thanks for clarifying the position. It is unwise to scare the people 
Without an evidence.


DR. Bapna

----- Original Message -----
From: Suresh kumar <skgup@hotmail.com>
To: <india-drug@usa.healthnet.org>
Sent: Wednesday, February 05, 2003 8:06 PM
Subject: [india-drug] Response to Toxicity of nimesulide



 Response to Toxicity of nimesulide
 ----------------------------------

 Dear Pipasha,
 I have read your reply in response to Dr. Bapna s E mail. You have
 quoted me for 15-20% ADRs. My reply was not at all for nimesulide. I
 had mentioned this in context of general ADRs due to NSAIDs. I am
 quoting the figures from ARAMIS reports which has the following
 message. The database from Arthritis Rheumatism and aging Medical
 Information Systems (ARAMIS) indicate 25% of all adverse drug 
Reactions being attributed to NSAIDs induced toxicity (Singh, 2000). I
agree with Prof. Bapna and Prof. Dandiya that withdrawl of a drug
should depend on the evidence of ADRs in a particular country. Of
course we need to  strengthen the Pharmacovigilance system in the
country.
Thanks
 With Regards
 Dr. S.K.Gupta

 Prof.S.K.Gupta
 Head, Dept. of Pharmacology;
Chief, National Pharmacovigilance Centre
All India Institute of Medical Sciences,
 New Delhi, India
 Pin Code-110029
 Tel.: 91-11-6593282, 6593633 (O)
 Fax: 91-11-6862663, 6521041
Email: skgup@hotmail.com



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