[e-farmacos] WHO Pharmaceuticals Newsletter No.1, 2007

["Canas, Martin" <macanas@netverk.com.ar>]

Estimadas y estimados,

La OMS ha publicado  el WHO Pharmaceuticals Newsletter (No.1, 2007). 

Con el siguiente indice:
Regulatory Matters

Aprotinin injection  --  Use limited to patients at increased risk of blood loss during heart surgery....1
Buflomedil  --  Higher dose tablets withdrawn due to risk of suicide ..1
Heparin  --  Delayed onset of heparin-induced thrombocytopenia..1
Methadone  --  Risk of QT prolongation and Torsades de pointes...1
Quinine  --  Consumers cautioned against off-label use in treating leg cramps...2
Rituximab  --  Fatal PML following off-label use in systemic lupus erythematosus (SLE)...2
Sodium phosphate oral solution  --  Electrolyte and renal function disturbances in the elderly...3
Topical anaesthetic creams  --  Pharmacies warned to cease compounding standardized versions.. 3

Safety of medicines

Cough and cold medications  --  Deaths in infants reviewed...4
3,4 diaminopyridine (DAP)  --  Not for treating fatigue in multiple sclerosis patients...4
Gefitinib  --  No survival advantage; increased risk of tumour haemorrhage...4
Leflunomide  --  Reports of interstitial lung disease...5
Tramadol  --  Withdrawal reactions may be a bigger problem than previously thought...5
Tumour necrosis factor (TNF)-Î inhibitors  --  Increased risk of malignancy...5

Feature

The need for a generic form for spontaneous reporting of drug related problems...7

proximamente disponible en:
http://www.who.int/medicines/publications/newsletter/en/index.html

Saludos,

Martin

Martin Canas
GAPURMED
La Plata 
(Argentina)
macanas@netverk.com.ar