[e-farmacos] WHO Drug Information Vol 18 Num 4

["Canas, Martin" <macanas@netverk.com.ar>]

Estimadas y estimados,

Esta disponible un nuevo numero de  WHO Drug Information,
Vol 18 Nº 4 

Drug Management
-   Cost containment and generic substitution 

-   Generic substitution in Finland

Safety and Efficacy Issues
-   Australian experience with pneumococcal conjugate vaccine

-   Overdose and tricyclic antidepressants

-   Terbinafine and blood discrasias

-   Cholinesterase inhibitors and cardiac arrhythmias

-   Lamotrigine: hormonal contraceptives decrease serum levels

-   Transdermal fentanyl and respiratory arrest in adolescents 

-   Infliximab and etanercept: serious infections and tuberculosis

-   Medication error alert

Current Topics
-   International standard for genetic testing 

-   Selective reporting and clinical trial registration 

-   Trials registration policy

-   National Library of Medicine trials registration

Regulatory and Safety Action
-   Antidepressants and suicidality in children and adolescents 

-   Withdrawal of rofecoxib

-   Regulations for COX-2 inhibitors

-   Southern hemisphere influenza vaccines 2005

-   European regulation for paediatric medicinal products 

-   Ephedrine and pseudoephedrine to become controlled drugs 

-   Epoetin alfa and blood clot formation in cancer patients

-   Mifepristone labelling changes 

-   TNF-blocking agents and serious infections 

-   Long-term use of Depo-Provera® and bone density loss 

-   Duloxetine approved for neuropathic pain associated with diabetes

-   Aripiprazole approved for acute bipolar mania 

HIV Medicines
-   3 by 5 strategy: improving access to paediatric HIV medicines

-   Urgent need for paediatric antirretroviral formulations 

-   WHO prequalification: implications of delisting

-   Combining TB and HIV treatment to save lives

Recent Publications and Sources of Information

-   International Conference on Improving Use of Medicines 

-   Three new quality assurance guidelines endorsed by WHO Expert Committee

-   WHO Medicines Bookshelf

-   International network on HIV/AIDS for pharmacists 

-   Managing pharmaceuticals internationally

-   New brochure on adverse reaction reporting 

-   International chemical reference substances for malaria 

-   New physician guidelines on commercial relationships 

-   COHRED and Research into Action 

-   Evaluation of medicinal products in children 

-   Procurement of medicines in HIV 

-   New antimicrobial resistance website for the public

-   Therapeutic guidelines on dermatology 

-   International Pharmacopoeia available on CD-ROM 

-   Safety monitoring of herbal medicines 

-   Medicinal plant guidelines translated 

Disponible en: 
http://www.who.int/druginformation/vol18num4_2004/DI18-4.pdf

Saludos,

Martin

Martin Canas
GAPURMED
La Plata 
(Argentina)
macanas@netverk.com.ar