[e-farmacos] Documentacion sobre ibuprofeno (cont.)

["Tassoni, Silvia" <hoteo0@rosario.gov.ar>]

E-farmacos: Documentacion sobre ibuprofeno (cont.)
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Estimado Ever,

Esta informacion corresponde a la USP 23 NF 18 1995

Ibuprofen Tablets
Contain not less than 90.0 percent and not more than 110.0 percent of
the labeled amount of C13H18O2
Dissolution: Medium: pH 7.2 phosphate buffer; 900 ml
Apparatus 1: 150 rpm.
Time: 30 minutes
Procedure: determine the amount of C13H18O2 dissolved from ultraviolet
absorbances at the wavelength of maximum absorbance  at about 221 nm of
filtered portions of the solution under test, suitably diluted with
Dissolution Medium, if neccesary, in comparison with a Standard solution
having a known concentration of USP Ibuprofen RS in the same medium. 
Tolerance: Not less than 70% (Q) of the labeled amount of C13H18O2 is
dissolved in 30 minutes.

Espero te resulte util.


Saludos,

Dra. Silvia Tassoni
Comision Municipal de Medicamentos
Rosario
(Argentina)
hoteo0@rosario.gov.ar


[NOTA: Mensaje sin acentos ni caracteres especiales.]
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