[e-drug] Creating off-label uses? (2)

["Larry Sasich" <lsasich@lecom.edu>]

E-DRUG: Creating off-label uses? (2)
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dear E-druggers,

In response to Don Light's question on off-label drug use. We will be
using Thomas Moore's "Deadly Medicine" published in 1995 by Simon &
Shuster as the basis for an elective course for pharmacy students in the
politics of pharmaceuticals.  

This book carefully documents the politics behind the development of the anti-arrhythmics Tambocor and Enkaid to treat benign ventricular contractions, an off-label use, and the subsequent early termination of the Cardia Arrhythmia Suppression Trial (CAST) in the late 1980s due to excess deaths in the active treatment group.     

Best regards,

Larry

Larry D. Sasich, Pharm.D., MPH, FASHP
Acting Chair, 
Department of Pharmacy Practice
LECOM School of Pharmacy
1858 West Grandview Blvd
Erie, PA 16509-1025
Office: 814-866-8467
FAX: 814-866-8450
E-mail: lsasich@lecom.edu