[e-drug] Pharmacokinetics (3)

["Roger Klotz" <RKlotz@SPCLIN.com>]

E-DRUG: Pharmacokinetics (3)
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In the U.S. the terms are not official scientific/pharmaceutical terms, but
they are marketing terms put out by the pharmaceutical manufacturers.  The
term usually depends upon the product and manufacturer.  Generally long
acting is associated either with a long half-life or a product that is
designed (pharmaceutically) to slowly deliver the product over a longer
period then the short acting standard dosage form.  Sustained release is a
another term for a pharmaceutical dosage form that slowly releases a short
acting product (i.e. methylphenidate products).  Controlled release is being
used for products that are designed to produce a slow release for short
acting products that uses the new technology for producing a sustained
release product.

This nomenclature has caused problems because it is not official terminology
and therefore depends upon the product and manufacturer.  We really do need
to develop and official standard for these terms.  I have not checked the
USP recently, but I am aware there have been serious problems as a result of
the confusing terminology.

 Roger S. Klotz, R.Ph., BCNSP, FASCP, FACA, FCPhA
 President & CEO
 Specialized Clinical Services, Inc.
 15615 Alton Parkway Suite 200
 Irvine, Ca. 92618
 949-341-0336
 Fax# 949-341-0385
 Roger Klotz <RKlotz@SPCLIN.com
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